Associations between Intake of Folate, Methionine, and Vitamins B-12, B-6 and Prostate Cancer Risk in American Veterans

Table 3

ORs and 95%CI for the association between MTHFR gene polymorphisms* and PC risk.

	PC cases 𝑛=55	Controls 𝑛=192	OR (95%CI), 𝑃value
	Frequency (%)	Frequency (%)
MTHFR polymorphism C677T
CC (homo wild type)	36 (65.45)	103 (53.65)	1.0
CT (hetero) and TT (homo)	19 (34.55)	89 (46.35)	0.67 (0.34–1.31), 𝑃=0.23
MTHFR polymorphism A1298C
AA (homo wild type)	36 (65.45)	103 (53.37)	1.0
AC (hetero) and CC (homo)	19 (34.55)	90 (46.63)	0.70 (0.37–1.33), 𝑃=0.28

*Adjusted for age, race, BMI, and smoking status.