Research Article
Impact of Diabetes Status and Medication on Presentation, Treatment, and Outcome of Stage II Colon Cancer Patients
Table 1
Clinicopathological features of nondiabetes versus diabetes patients.
| | | All patients
| Patients without type 2 diabetes
| Patients with
type 2 diabetes
|
| | Median age in years (range) | 70.9 (20.5, 101.2) | 69.6 (20.5–101.2) | 74.0 (26.5–93.3) | | Sex | | | | | Female (%) | 497 (44.5%) | 400 (45.7%) | 97 (40.3%) | | Male (%) | 619 (55.5%) | 475 (54.3%) | 144 (59.7%) | | Site | | | | | Right colon (%) | 533 (47.8%) | 407 (46.5%) | 126 (52.3%) | | Left colon (%) | 583 (52.2%) | 467 (53.4%) | 115 (47.7%) | | T4 staging (%) | 176 (15.8%) | 131 (15.0%) | 45 (18.7%) | | <12 lymph nodes examined | 275 (24.6%) | 208 (23.8%) | 67 (27.8%) | | Poor differentiation (%) | 225 (20.2%) | 170 (19.4%) | 55 (22.8%) | | Lymphovascular invasion | 266 (23.8%) | 211 (24.1%) | 55 (22.8%) | | MSI status (%) | | | | | MSI-stable | 441 (39.5%) | 351 (40.1%) | 90 (37.3%) | | MSI-high | 114 (10.2%) | 92 (10.5%) | 22 (9.1%) | | Not done | 536 (48.0%) | 413 (47.2%) | 123 (51.0%) | | Unknown | 25 (2.2%) | 19 (2.2%) | 6 (2.5%) | | Emergency presentationa | 158 (14.2%) | 122 (13.9%) | 36 (14.9%) |
|
|
aEmergency presentation includes bowel perforation or bowel obstruction.
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