Impact of Diabetes Status and Medication on Presentation, Treatment, and Outcome of Stage II Colon Cancer Patients

Table 4

Univariate and multivariate analyses for recurrence-free survival.

Clinicopathological variable^a	Univariate model			Multivariate model
	HR^b	95% CI^c		HR^b	95% CI^c
Age
60 years	1.00	0.87–2.02	0.184	1.00	0.86–2.14	0.193
60 years	1.33			1.35
Diabetes
No diabetes	1.00	0.74–1.60	0.667	1.00	0.65–1.49	0.93
Diabetes	1.09			0.98
T stage
T3	1.00	1.65–3.41	<0.001	1.00	1.36–2.94	<0.001
T4	2.37			2.00
Lymph node yield
12	1.00	1.01–2.02	0.043	1.00	0.89–1.89	0.169
12	1.43			1.30
Lymphovascular invasion
Absent	1.00	1.57–3.12	<0.001	1.00	1.43–2.89	<0.001
Present	2.21			2.03
Emergency presentation
No	1.00	1.21–2.75	0.004	1.00	1.07–2.49	0.022
Yes	1.82			1.63

^aMicrosatellite instability status was not included in the regression models for lack of complete data (complete data in 52% of patients).
^bHazard ratio.
^cConfidence interval.