Research Article
A Retrospective Observational Study on Disease Characteristics and Treatment Patterns of Giant Cell Tumor of the Bone in China
Table 4
Postoperative recurrence-free survival for primary GCTB diagnosis (EAS).
| Item | | Event, (%) | Event censored, (%) | Median time to recurrence (months) | 2-year recurrence rate (%) (95% CI) |
| Total | 627 | 197 (31.4) | 430 (68.6) | 75.8 | 29.2 (25.3, 33.5) | Sex | | | | | | Male | 322 | 107 (33.2) | 215 (66.8) | 72.2 | 28.7 (23.5, 34.7) | Female | 305 | 90 (29.5) | 215 (70.5) | 92.4 | 29.7 (24.2, 36.2) | Age group | | | | | | <18 | 25 | 9 (36.0) | 16 (64.0) | 92.4 | 31.2 (16.0, 55.0) | 18 to 40 | 475 | 157 (33.1) | 318 (66.9) | 72.2 | 29.7 (25.3, 34.7) | >40 | 127 | 31 (24.4) | 96 (75.6) | 130.9 | 26.9 (18.8, 37.6) | Place of residence | | | | | | Beijing | 112 | 18 (16.1) | 94 (83.9) | NE | 16.4 (10.0, 26.4) | Others | 515 | 179 (34.8) | 336 (65.2) | 58.5 | 31.8 (27.5, 36.7) | Hospital where GCTB was first diagnosed | | | | | | JST | 436 | 29 (6.7) | 407 (93.3) | NE | 5.4 (3.3, 8.5) | Non-JST | 191 | 168 (88.0) | 23 (12.0) | 16.5 | 68.0 (61.3, 74.6) | Surgery type | | | | | | Curettage | 442 | 183 (41.4) | 259 (58.6) | 45.4 | 37.0 (32.1, 42.3) | Resection | 185 | 14 (7.6) | 171 (92.4) | NE | 6.4 (3.3, 12.2) | Amputation | 0 | 0 (0.0) | — | — | — | Others | 0 | 0 (0.0) | — | — | — | Target lesion anatomic site | | | | | | Axial bone | 78 | 14 (17.9) | 64 (82.1) | NE | 17.6 (9.7, 30.7) | Extremities | 548 | 183 (33.4) | 365 (66.6) | 72.2 | 30.8 (26.6, 35.5) |
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CI = confidence interval; EAS = efficacy analysis set; GCTB = giant cell tumor of the bone; JST = Ji Shui Tan; NE = nonestimable.
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