Abstract
A synthesis of 11-(piperazin-1yl)-5 H-dibenzo[b,e][1,4]diazepine on kilo scale without any chromatographic purification step is reported. Key steps involved are Ullmann condensation, catalytic hydrogenation, and catalyzed cyclization.
Open Access
Synthesis of 11-(Piperazin-1-yl)-5H-dibenzo[b,e] [1,4]diazepine on Kilo Scale
Received26 Jan 2010
Accepted22 Apr 2010
Copyright
Copyright © 2011 Hindawi Publishing Corporation.
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