Genistein Derivatives Regioisomerically Substituted at 7-O- and 4′-O- Have Different Effect on the Cell Cycle

Table 1

IC₅₀ value of proliferation inhibition calculated on the base of MTT assay.

IC50 (µM)
	HCT 116 wt	DU 145
Gen-2′	>100	>100
Gen-3′	25.58±10.81	21.60±10.92
Gen-5′	7.19±2.04	6.42±2.87
Ram-2′	0.07±0.03	0.37±0.10
Ram-3′	13.61±2.20	12.59±5.43
Ram-5′	7.17±1.76	6.04±1.25