Synthesis and Antiviral Activity of Hydrogenated Ferulic Acid Derivatives

Table 1

Antiviral activities of the title compounds at 500 μg/mL.

Compound	R1	R2	Anti-TMV activities
			Protection effect	Curative effect
4a	m-MeO	Benzyl	0	24.2
4b	m-NO2	Benzyl	10.4	0
4c	m-NO2	Propynyl	0	0
4d	p-NO2	Benzyl	0	0
4e	p-benzyloxy	Benzyl	0	12.3
4f	p-benzyloxy	Propynyl	15.2	28.9
4g	p-benzyloxy	Allyl	22.8	20.7
Ribavirin			32.6	38.5