Design, Synthesis, and Pharmacological Screening of Novel Porphyrin Derivatives

Table 5

Cytotoxicity (IC₅₀) of tested dyes on different cell lines.

Dye number	IC50
	HePG2	WI-38	VERO	MCF-7
2a	60	59	74	64
2b	80	70	60	54
2c	66	100	51	39
2d	76	64	42	36
2e	79	68	56	60
2f	63	58	33	27
5-Flu.	9	zero	7	zero

(IC₅₀, (μg/mL): 1–10 (very strong), 11–25 (strong), 26–50 (moderate), 51–100 (weak), 100–200 (very weak), above 200 (noncytotoxic)).