DNA Binding and Cleavage Activities of Na[B(Glu)(OH)2]·2H2O, Na[B(Cit)(OH)2]·2H2O, Li[B(Sal)(OH)2], and Mg[B(Sal)(OH)2]·2H2O Complexes
Figure 2
DNA cleavage by the complexes 1, 2, 3, and 4 obtained using agarose gel electrophoresis showing the chemical activity of the DNA incubated at 37°C for 3 h with different concentrations of complexes 1, 2, 3, and 4 in the presence of H2O2 as an oxidizing agent: lane 4, control (DNA); lane 5, DNA + H2O2 (60 μM); lanes 1, 2, and 3, DNA + H2O2 (60 μM) + complex 1 (5, 25, and 50 μM); lanes 6, 7, 8, DNA + H2O2 (60 μM) + complex 2 (5, 25, and 50 μM); lanes 9, 10, and 11, DNA + H2O2 (60 μM) + complex 3 (5, 25, and 50 μM); lane 12, control (DNA); lane 13, DNA + H2O2 (60 μM); lanes 14, 15, and 16, DNA + H2O2 (60 μM) + complex 4 (5, 25, and 50 μM).
