Table 3: Statistical evaluation of the results obtained by the proposed and reference methods for the determination of LAM in tablets.

Pharmaceutical preparationProposed methodReference methodd
Mean ± SDaRSD% Mean ± SDaRSD%

Lamictal 100 tablets100.08 ± 0.820.820.6799.62 ± 0.740.740.550.941.22
Lamictal 50 tablets99.58 ± 0.690.700.47100.14 ± 0.500.500.251.471.88
Lamictal 25 tablets99.68 ± 0.620.620.3899.85 ± 0.830.830.691.891.82
Lamotrigine 100 tablets99.80 ± 0.580.580.3499.85 ± 0.460.460.210.131.62
Lamotrigine 50 tablets99.91 ± 0.740.740.55100.01 ± 1.151.151.320.172.40
Lamotrigine 25 tablets99.63 ± 0.760.760.5899.41 ± 0.960.970.930.391.60
Laptorgine 200 tablets99.77 ± 0.580.580.3499.39 ± 1.041.051.080.733.20
Laptorgine 25 tablets99.62 ± 0.820.820.6799.45 ± 0.800.800.640.361.05
Larogen 100 tablets99.52 ± 1.381.391.9099.76 ± 0.850.850.730.342.60

Mean %R ± SD of 5 experiments.
bVariance ( ).
cThe theoretical and values, 2.31 and 6.39, respectively at .
d[9].