Table 2: Synthesis of 2H-indazolo[2,1-b]phthalazine-trione derivatives under grinding.

634510.fig.003

EntryArR (min)ProductYield (%)a

1C6H5CH32a91
24-CH3C6H4CH32b90
34-CH3OC6H4CH35c88
44-FC6H4CH32d87
54-ClC6H4CH32e86
62-ClC6H4CH32f83
74-BrC6H4CH32g85
84-NO2C6H4CH32h92
94-OHC6H4H5i86
104-(CH3)2NC6H4H5j84
112-NaphthylH2k89
124-CH3C6H4H2l90

Isolated yields.