Synthesis, Antibacterial, and Antifungal Activities of Novel Pyridazino Carbazoles

Table 1

Antimicrobial activities of compound 2–9 in terms of minimum inhibitory concentration (μg/mL).

Tested compounds	MRSA		S. typhi		C. albicans
	MIC50	MIC100	MIC50	MIC100	MIC50	MIC100
2	256	>512	512	>512	16–32	64
3	8	12	512	>512	16	32
4	512	>512	256	>512	128	512
5	128	512	256	512	16	64
6	128	256	14	32	512	>512
7	>512	>512	256	512	32	64
8	4	12	>512	>512	256	512
9	512	>512	128	256	16	32
Ciprofloxacin	>512	>512	>512	>512	—	—
Ketoconazole	—	—	—	—	14	32

DMSO: negative control.