Development and Validation of HLPC Method for the Estimation of Lamotrigine in Bulk and Pharmaceutical Formulations

Table 4

Study of robustness of the proposed method.

S. no.	Flow rate mL/min.	Plate count	Tailing factor	% mobile phase	Plate count	Tailing factor
1	0.6	2573.0	1.6	10% less	2250.9	1.6
2	0.7	2365.7	1.5	Actual	2365.7	1.5
3	0.8	2461.1	1.5	10% high	2166.3	1.5

^∗Results for actual flow (0.7 mL/min) have been considered from assay standard.
^∗Results for actual mobile phase composition (60 : 40 acetonitrile : buffer) have been considered.