Research Article

Quantitative Structure Activity Relationship Studies of Topoisomerase I Inhibitors as Potent Antibreast Cancer Agents

Table 3

Statistical data of the independent variable illustrating the significance in terms of statistical parameters.

CoefficientJackknife -valueT-probabilityCovariance SE

Molecular mass (subst.3)−0.0230.001−15.4081.4650.001
Molecular surface area (subst.2)−1.1460.169−8.2956.6220.138
Number of H-bond acceptors (subst.4)−0.1850.073−2.3630.0280.078