Research Article
Iodine-Mediated Neutral and Selective N-Boc Deprotection
Table 2
Iodine-mediated deprotection of N-tert butylcarbamates (1) (Scheme 1).
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aAll the reactions were carried out using the N-tert butylcarbamate 1 (1.0 mmol) and iodine (0.08 mmol) at room temperature. bIsolated yield. cAll the reactions were carried out using DCM (5 mL) at room temperature for 5-6 h. |