Direct and Indirect Drug Design Approaches for the Development of Novel Tricyclic Antipsychotics: Potential 5-HT_2A Antagonist

Figure 1

Limitations of current antipsychotic therapies (a) loxapine; (b) clothiapine; (c) clozapine; (d) olanzapine.

(a)

(b)

(c)

(d)