Pharmacological Profile of Quinoxalinone

<table class="table-group" id="tab8"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td align="left">Compound</td><td align="center">R<sub>3</sub></td><td align="center"><svg height="15.65" id="M8" style="vertical-align:-3.39069pt" version="1.1" viewbox="0 0 29.6875 15.65" width="29.6875" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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<g transform="matrix(.012,-0,0,-.012,16.962,15.45)"><path d="M153 550l-26 -186q79 31 111 31q90 0 141.5 -51t51.5 -119q0 -93 -89 -166q-85 -69 -173 -71q-32 0 -61.5 11.5t-41.5 23.5q-18 17 -17 34q2 16 22 33q14 9 26 -1q61 -50 124 -50q60 0 93 43.5t33 104.5q0 69 -41.5 110t-121.5 41q-53 0 -102 -20l38 305h286l6 -8
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<g transform="matrix(.017,-0,0,-.017,.062,7.675)"><path d="M538 96q-38 -45 -84 -76.5t-71 -31.5q-44 0 -15 117q12 49 18 89h-2q-99 -128 -163 -178q-36 -28 -70 -28q-26 0 -44 38h-2q-16 -69 -16 -129q0 -43 11 -75.5t24 -42.5l1 -6q-7 -12 -24.5 -23t-37.5 -11q-40 0 -40 76q0 52 35 202l94 407l78 24l5 -5q-32 -122 -72 -310
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</svg>M)</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td align="left"><b>51a</b></td><td align="center">H</td><td align="center">2.02</td></tr><tr><td align="left"><b>51b</b></td><td align="center">CH<sub>3</sub></td><td align="center">0.2</td></tr><tr><td align="left"><b>51c</b></td><td align="center">C<sub>2</sub>H<sub>5</sub></td><td align="center">5.0</td></tr><tr><td align="left"><b>51d</b></td><td align="center">CH<sub>2</sub>CH<sub>2</sub>SCH<sub>3</sub></td><td align="center">&gt;100</td></tr><tr><td align="left"><b>51e</b></td><td align="center">CH<sub>2</sub>COOCH<sub>3</sub></td><td align="center">&gt;100</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Journal of Chemistry

tab8

Table 8

Table 8: Pharmacological Profile of Quinoxalinone 