Journal of Chemistry

Research Article

Green Route for Efficient Synthesis of Novel Amino Acid Schiff Bases as Potent Antibacterial and Antifungal Agents and Evaluation of Cytotoxic Effects

Table 2

Antibacterial and antifungal evaluation of the synthesized compounds (4a–p).
CompoundMIC (ug/mL)
Bacterial strainsFungal strains
Pseudomonas aeruginosa Bacillus licheniformis Staphylococcus aureus Micrococcus luteus Escherichia coli Aspergillus sp.Penicillium sp.Alternaria brassicicola Chaetomium orium Lycopodium sp.
4a− −− −100010001000− −− −− −− −1000
4b− −− −− −− −− −− −− −− −− −− −
4c10001000− −− −− −>1000− −− −− −− −
4d− −− −− −500500− −− −− −− −− −
4e− −− −10005001000− −− −− −− −− −
4f− −− −− −− −− −− −− −− −− −− −
4g1000100010005005001000− −− −− −− −
4h− −1000− −5005001000− −10001000− −
4i− −1000− −500500− −100010001000− −
4j100010001000500− −− −− −− −− −− −
4k− −− −− −− −1000− −1000100010001000
4l1000− −− −500− −− −− −− −− −− −
4m10001000100050010001000100010001000− −
4n 1000− −− −1000>1000− −− −>1000− −
4o− −− −1000500− −− −− −− −− −− −
4p100010001000− −− −− −− −− −10001000
Solvent
DMSO		− −− −− −− −− −− −− −− −− −− −