Research Article

Green Route for Efficient Synthesis of Novel Amino Acid Schiff Bases as Potent Antibacterial and Antifungal Agents and Evaluation of Cytotoxic Effects

Table 3

Minimum inhibitory concentration for fungi.

CompoundMIC (ug/mL)
Aspergillus sp.Penicillium sp.Alternaria brassicicola Chaetomium orium Lycopodium sp.
25050010002505001000250500100025050010002505001000

4a+++++++++++++− − *
4b+++++++++++++++
4c++− − * ++++++++++++
4d+++++++++++++++
4e+++++++++++++++
4f+++++++++++++++
4g+++++++++++++
4h++− − * +++++− − * ++− − * +++
4i+++++− − * ++− − * ++− − * +++
4j+++++++++++++++
4k+++++− − * ++− − * ++− − * ++− − *
4l++− − * +++++++++++
4m++− − * ++− − * ++++− − * ++
4n++− − * +++++++− − * ++
4o+++++++++++++
4p++++++++++− − * ++− − *
Solvent
DMSO
+++++++++++++++
Itraconazole − − − − − −− − −

Moderately active (zone of inhibition 8–10 mm).