Journal of Chemistry

Research Article

Green Route for Efficient Synthesis of Novel Amino Acid Schiff Bases as Potent Antibacterial and Antifungal Agents and Evaluation of Cytotoxic Effects

Table 4

Minimum inhibitory concentration for bacteria.
CompoundMIC (ug/mL)
Pseudomonas aeruginosa Bacillus licheniformis Staphylococcus aureus Micrococcus luteus Escherichia coli
25050010002505001000250500100025050010002505001000
4a+++++++−− − * +−− − * +−− − *
4b+++++++++++++++
4c+−− − * +−− − * +++++++−− − *
4d++++++++++− − * − − * +− − * − − *
4e+++++++−− − * +− − * − − * +−− − *
4f+++++++++++++++
4g+−− − * +−− − * +−− − * +− − * − − * −− − * − − *
4h++++−− − * +++−− − * − − * +− − * − − *
4i++++−− − * +++−− − * − − * −− − * − − *
4j+−− − * ++− − * ++− − * −− − * − − * +− − * − − *
4k+++++++++++++−− − *
4l++− − * +++++++− − * − − * +++
4m+−− − * ++− − * +−− −++++−− − *
4n++−++− − * ++++− − * − − * +++
4o++−++++−− − * +− − * − − * ++− − *
4p+−− − * ++− − * +−− − * ++++++
Solvent
DMSO		+++++++++++++++
Streptomycin− − − −+++− − − −
Gentamycin− − −− − −− − − −− − − −− − − −
+: inactive (zone of inhibition < 6 mm); −: slightly active (zone of inhibition 6–8 mm); − −: moderately active (zone of inhibition 8–10 mm); − − − −: highly active (zone of inhibition > 10 mm); filled part showing MIC for particular organism.