Research Article

Simultaneous HPLC Determination of Chlordiazepoxide and Mebeverine HCl in the Presence of Their Degradation Products and Impurities

Table 3

Precision data for the determination of CDO and MBV by the proposed method.

CompoundConc. (µg/mL)Intraday precisionInterday precision
Mean % found ± SD% RSDMean % found ± SD% RSD

CDO1.0100.10 ± 0.910.9199.45 ± 1.071.08
50.0100.77 ± 1.441.4399.15 ± 0.950.95
100.0100.44 ± 0.550.55100.50 ± 0.640.63

MBV10.0100.83 ± 0.630.6299.09 ± 0.810.82
100.0100.41 ± 0.670.6799.49 ± 1.331.33
200.099.75 ± 0.530.53100.42 ± 1.091.09