Simultaneous HPLC Determination of Chlordiazepoxide and Mebeverine HCl in the Presence of Their Degradation Products and Impurities

Table 5

Final system suitability test parameters for the proposed method.

Compound	Number of theoretical plates ()	Retention factor ()	Tailing factor ()
CDO	2778	0.42	1.44
MBV	2542	1.13	1.55
VER	2433	0.15	1.52
ACB	2326	1.40	1.48
Compounds^a	Resolution ()	Selectivity factor ()
CDO/VER	2.64	2.80
CDO/MBV	5.04	2.69
MBV/ACB	1.45	1.24

Resolution and selectivity factor were calculated for each two adjacent peaks.
Calculations were done according to USP guidelines [3].