Oxidation of Enrofloxacin with Permanganate: Kinetics, Multivariate Effects, Identification of Oxidation Products, and Determination of Residual Antibacterial Activity

Figure 1

The time course of ENR (10 μM) oxidation with Mn(VII) (500 μM) at pH 4.0–10.0, acetate buffer for pH 4-5, phosphate buffer for pH 6–8, borate buffer for pH 9-10 (a); the time course of ENR (10 μM) oxidation with Mn(VII) (500 μM) in solutions with different buffers. Experimental condition: [ENR]₀ = 10 μM,  μM, pH 7.0, and °C (b).

(a)

(b)