Reaction of Nitrilimines with Pyruvaldehyde Hydrazones: Synthesis and Antimicrobial Evaluation of Some New 1,2,4-Triazole Derivatives

Table 1

Antimicrobial screening results of the tested compounds^*.

Comp. number	Antibacterial activity					Antifungal activity
	Enterococci	E. coli	Staph. aureus	Klebsiella spp.	Proteus spp.	Candida albicans	Aspergillus niger
4a	12	16	14	13	9	13	11
4b	16	16	11	5	12	14	16
4c	17	12	10	12	14	16	15
4d	15	17	15	15	11	14	10
4e	14	15	14	17	10	17	7
4f	12	11	12	16	6	15	8
4g	17	14	10	13	17	13	12
4h	16	12	16	15	7	14	14
4i	14	13	15	11	12	12	10
4j	11	10	13	12	6	11	7
6b	12	12	11	10	11	15	12
6d	9	14	8	12	13	8	14
6g	18	17	16	17	16	17	16
6i	15	13	12	14	12	11	9
DMF	—	—	—	—	—	—	—

Calculated as average of three values.