Derivative Spectrophotometric Methods for the Analysis and Stability Studies of Colistin Sulphate

Table 1

Linearity data for the developed methods.

Parameter	Zero-order	1st derivative	2nd derivative
	280 nm	298 nm	318 nm
	0.00027 ± 0.000	0.000005 ± 0.000	0.0089 ± 0.0008
	0.015 ± 0.089	−0.0006 ± 0.0017	−0.43 ± 2.7
LOD	335 IU/mL	343 IU/mL	239 IU/mL
LOQ	1015 IU/mL	1040 IU/mL	725 IU/mL
	0.998	0.998	0.999