Synthesis and Evaluation of Antimicrobial Activity of Nitrones from Derivatives of Aryl-Substituted Dihydroisoquinoline

Table 2

Antimicrobial activity of synthesized compounds 4a–c^(a,b,c) compared to an antibiotic like penicillin (P).

Compounds	Inhibition  zone  diameter  (mm)
	B.  thuringiensis	E.  coli	B.  subtilis	K.  pneumoniae	E.  faecalis
4a	15 ± 0.35	12 ± 0.14	—	—	—
4b	—	—	12 ± 1.06	—	—
4c	—	12 ± 0.53	—	—	—
P	R	14 ± 0.70	14 ± 0.25	10 ± 0.35	14 ± 0.00

B. thuringiensis: Bacillus thuringiensis; E. coli: Escherichia coli; B.  subtilis: Bacillus subtilis; K. pneumoniae: Klebsiella pneumoniae; E. faecalis: Enterococcus faecalis; R: resistant.
^aSample concentration: 8 mg/Ml. Sample volume 1000 µL/well.
^bResults are calculated after subtraction of MeOH activity.
^cNot active (inhibition zone < 2 mm); weak activity (2–8 mm); moderate activity (9–15 mm); strong activity (>15 mm).