Synthesis and In Vitro Evaluation of New Thiosemicarbazone Derivatives as Potential Antimicrobial Agents

Scheme 1

The synthetic route for the preparation of the thiosemicarbazone derivatives (1–12). Reagents and conditions: (i) NH₂NH₂·H₂O, ethanol, rt, 4 h; (ii) ArCHO, ethanol, reflux, 6 h.