Synthesis and In Vitro Evaluation of New Thiosemicarbazone Derivatives as Potential Antimicrobial Agents

Table 3

Anticandidal activity of the thiosemicarbazone derivatives (MIC values in µg/mL).

Compound	A	B	C	D
1	400	400	200	200
2	400	200	200	200
3	400	400	400	200
4	400	400	200	200
5	400	200	200	200
6	400	400	200	200
7	400	400	200	200
8	400	400	200	200
9	400	400	200	200
10	400	400	200	200
11	400	400	400	200
12	400	400	400	200
Ketoconazole	200	200	3.125	50

A: C. albicans (ATCC 90028), B: C. glabrata (ATCC 90030), C: C. krusei (ATCC 6258), and D: C. parapsilosis (ATCC 22019).