Highly Selective Synthesis of Chlorophenols under Microwave Irradiation

Table 1

Oxychlorination of phenols under microwave irradiation.

Entry	Substrate (0.78 M)	Product	Time (min)	Conversion (%)	Selectivity (%)
1			60	93.4	96.6
2			20	97.2	98.8
3			20	90.1	79.3
4			20	93.5	99.4
5			50	94.7	93.5
6			10	100	99.8
7			20	96.5	91.7

Conditions: microwave irradiation; solvent, aqueous hydrochloric acid solution (6 mol/L); reaction temperature (50°C). Conversion and selectivity were determined by GC.