Research Article
Antiproliferative Activity Evaluation of a Series of N-1,3-Benzothiazol-2-ylbenzamides as Novel Apoptosis Inducers
Table 2
Antiproliferative activity (% inhibition, MTT assay) of the target compounds 1a–n and 2a–e over HepG2 and MCF-7 cells.
| | HepG2 | MCF-7 | | Inhibition % | Inhibition % | | (10 μM) | (10 μM) |
| 1a | 34 ± 3 | 20 ± 1 | 1b | 70 ± 1 | 24 ± 2 | 1c | 52 ± 3 | 26 ± 15 | 1d | 0 ± 10 | 0 ± 2 | 1e | 45 ± 2 | 39 ± 1 | 1f | 80 ± 2 | 56 ± 2 | 1g | 36 ± 1 | 40 ± 1 | 1h | 64 ± 1 | 22 ± 2 | 1i | 76 ± 1 | 46 ± 1 | 1j | 39 ± 2 | 31 ± 8 | 1k | 64 ± 2 | 64 ± 6 | 1l | 46 ± 7 | 41 ± 8 | 1m | 33 ± 4 | 10 ± 5 | 1n | 32 ± 5 | 25 ± 12 | 2a | 5 ± 3 | 14 ± 5 | 2b | 23 ± 15 | 28 ± 26 | 2c | 58 ± 5 | 35 ± 14 | 2d | 58 ± 3 | 54 ± 24 | 2e | 20 ± 8 | 40 ± 10 |
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Data are presented as the means ± SD of three independent experiments.
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