Antiproliferative Activity Evaluation of a Series of N-1,3-Benzothiazol-2-ylbenzamides as Novel Apoptosis Inducers

Table 2

Antiproliferative activity (% inhibition, MTT assay) of the target compounds 1a–n and 2a–e over HepG2 and MCF-7 cells.

	HepG2	MCF-7
	Inhibition %	Inhibition %
	(10 μM)	(10 μM)
1a	34 ± 3	20 ± 1
1b	70 ± 1	24 ± 2
1c	52 ± 3	26 ± 15
1d	0 ± 10	0 ± 2
1e	45 ± 2	39 ± 1
1f	80 ± 2	56 ± 2
1g	36 ± 1	40 ± 1
1h	64 ± 1	22 ± 2
1i	76 ± 1	46 ± 1
1j	39 ± 2	31 ± 8
1k	64 ± 2	64 ± 6
1l	46 ± 7	41 ± 8
1m	33 ± 4	10 ± 5
1n	32 ± 5	25 ± 12
2a	5 ± 3	14 ± 5
2b	23 ± 15	28 ± 26
2c	58 ± 5	35 ± 14
2d	58 ± 3	54 ± 24
2e	20 ± 8	40 ± 10

Data are presented as the means ± SD of three independent experiments.