Research Article

Ligand Synthesis Catalyst and Complex Metal Ion: Multicomponent Synthesis of 1,3-Bis(4-phenyl-[1,2,3]triazol-1-yl)-propan-2-ol Copper(I) Complex and Application in Copper-Catalyzed Alkyne-Azide Cycloaddition

Table 2

Synthesis of triazoles catalyzed by copper complex 4 (see Scheme 3).

CompoundR% yield

6Ph100
795
8CH2O(4-Br)C6H434
9CH2O(4-Cl)C6H447
10CH2O(4-OCH3)C6H495
11CH2O(4-CH3)C6H498
12CH2OC6H594
13CH2O(4-CHO)C6H494
14CH2OCONH(CH2)3CH393