Research Article
Novel Palladium(II) and Platinum(II) Complexes with a Fluoropiperazinyl Based Ligand Exhibiting High Cytotoxicity and Anticancer Activity In Vitro
Table 2
MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) results, the values shown are .
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The results are shown in terms of IC50 values (the concentration needed to inhibit 50% of the cellular proliferation). For comparison purposes, the cytotoxicity of cisplatin, a standard antitumor drug was tested under the same conditions. +The time it took for the drug to affect cell viability. After 72 h of drug addition, the drug killed at most 15% of the cells at 50 μg/mL. |