Research Article
Ultrasonic-Assisted Synthesis of Two t-Butoxycarbonylamino Cephalosporin Intermediates on SiO2
Table 1
Comparison of three methods for the synthesis of Boc-ACLE.
| Number | Catalyst | Reaction time | Solvent | Yield% |
| 1 | NSA | 12 h | CH2Cl2 | 51 [4] | 2 | TEBA | 10 h | Dioxane/H2O | 80 [5] | 3 | Catalyst-free | 8 h | THF | 15 [6] |
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The HPLC assay indicated the yield was 15% according to the reported methods.
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