Research Article
Confirmed Mechanism for 1,8-Diaminonaphthalene and Ethyl Aroylpyrovate Derivatives Reaction, DFT/B3LYP, and Antimicrobial Activity of the Products
Table 3
The activity of the tested compounds 12a–e and 21a–e against two fungi species.
| | Compound number | Aspergillus niger | Geotrichum candidum | Compound number | Aspergillus niger | Geotrichum candidum |
| | 12a | 19.4 ± 0.63 (83.3%) | 18.1 ± 0.58 (71.8%) | 21a | 17.3 ± 1.2 (74.2%) | 19.3 ± 1.2 (76.6%) | | 12b | 23.7 ± 0.72 (101.7%) | 24.4 ± 1.2 (96.8%) | 21b | 15.5 ± 2.1 (66.5%) | 14.2 ± 2.1 (56.3%) | | 12c | 19.6 ± 0.63 (84.4%) | 21.6 ± 0.63 (85.71%) | 21c | 24.1 ± 1.2 (103.4%) | 23.6 ± 1.2 (93.7%) | | 12d | 22.8 ± 1.2 (97.9%) | 20.7 ± 0.72 (82.1%) | 21d | 19.2 ± 0.72 (82.4%) | 17.3 ± 0.72 (68.7%) | | 12e | 19.4 ± 0.63 (83.3%) | 25.6 ± 0.63 (101.6%) | 21e | 12.9 ± 0.72 (55.4%) | 18.5 ± 0.72 (73.4%) | | Amphotericin B | 23.3 ± 0.58 | 25.2 ± 0.72 | Amphotericin B | 23.3 ± 0.58 | 25.2 ± 0.72 |
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Data are expressed in the form of mean ± SD.
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