Research Article
Synthesis and Evaluation of the Antibacterial and Antioxidant Activities of Some Novel Chloroquinoline Analogs
Table 1
The inhibition zone of synthetic compounds in mm (mean ± SD).
| Compounds | Concentrations in µg/mL | Bacteria strains and zone of inhibition in mm | E. coli | S. aureus | P. aeruginosa | S. pyogenes |
| 5 | 100 | 7.00 ± 0.04 | 9.00 ± 0.03 | 9.00 ± 0.04 | 8.00 ± 0.01 | 200 | 9.00 ± 0.01 | 11.00 ± 0.03 | 11.00 ± 0.03 | 10.00 ± 0.04 | 6 | 100 | 9.00 ± 0.00 | 8.00 ± 0.01 | 7.00 ± 0.04 | 7.00 ± 0.01 | 200 | 11.00 ± 0.04 | 9.00 ± 0.00 | 8.00 ± 0.01 | 8.00 ± 0.03 | 7 | 100 | 8.00 ± 0.00 | 8.00 ± 0.00 | 8.00 ± 0.03 | 10.00 ± 0.04 | 200 | 10.00 ± 0.01 | 9.00 ± 0.01 | 9.00 ± 0.04 | 11.00 ± 0.02 | 8 | 100 | 10.00 ± 0.00 | 8.00 ± 0.01 | 9.00 ± 0.04 | 7.00 ± 0.03 | 200 | 12.00 ± 0.00 | 9.00 ± 0.04 | 10.00 ± 0.00 | 10.00 ± 0.03 | 12 | 100 | 8.00 ± 0.02 | 7.00 ± 0.01 | 8.00 ± 0.00 | 8.00 ± 0.02 | 200 | 9.00 ± 0.04 | 10.00 ± 0.01 | 8.00 ± 0.00 | 9.00 ± 0.02 | Amoxicillin | 100 | 16.00 ± 0.00 | 15.00 ± 0.01 | 16.00 ± 0.04 | 16.00 ± 0.03 | 200 | 18.00 ± 0.01 | 17.00 ± 0.01 | 18.00 ± 0.00 | 18.00 ± 0.03 |
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Results are mean ± SD of duplicate experiments. Amoxicillin was used as a positive control.
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