Synthesis and Evaluation of the Antibacterial and Antioxidant Activities of Some Novel Chloroquinoline Analogs

Table 7

Toxicity prediction of compounds 5–8 and 12 computed by ProTox II and OSIRIS Property Explorer.

Samples	Formula	LD50 (mg/kg)	Toxicity class	Organ toxicity
				Hepatotoxicity	Carcinogenicity	Immunotoxicity	Mutagenicity	Cytotoxicity
5	C10H4Cl2N2	5000	5	Inactive	Inactive	Inactive	Inactive	Inactive
6	C10H6Cl2N2O	705	4	Inactive	Inactive	Inactive	Inactive	Inactive
7	C11H8ClNO2	2190	5	Inactive	Active	Inactive	Inactive	Inactive
8	C12H10ClNO2	2190	5	Inactive	Active	Inactive	Inactive	Inactive
12	C10H5ClN2	1100	4	Inactive	Inactive	Inactive	Inactive	Inactive
Vosaroxin	C18H19N5O4S	500	4	Active	Inactive	Inactive	Inactive	Inactive