Research Article
Synthesis and Evaluation of the Antibacterial and Antioxidant Activities of Some Novel Chloroquinoline Analogs
Table 7
Toxicity prediction of compounds 5ā8 and 12 computed by ProTox II and OSIRIS Property Explorer.
| Samples | Formula | LD50 (mg/kg) | Toxicity class | Organ toxicity | Hepatotoxicity | Carcinogenicity | Immunotoxicity | Mutagenicity | Cytotoxicity |
| 5 | C10H4Cl2N2 | 5000 | 5 | Inactive | Inactive | Inactive | Inactive | Inactive | 6 | C10H6Cl2N2O | 705 | 4 | Inactive | Inactive | Inactive | Inactive | Inactive | 7 | C11H8ClNO2 | 2190 | 5 | Inactive | Active | Inactive | Inactive | Inactive | 8 | C12H10ClNO2 | 2190 | 5 | Inactive | Active | Inactive | Inactive | Inactive | 12 | C10H5ClN2 | 1100 | 4 | Inactive | Inactive | Inactive | Inactive | Inactive | Vosaroxin | C18H19N5O4S | 500 | 4 | Active | Inactive | Inactive | Inactive | Inactive |
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