Research Article

Protective Effect of Nano-Vitamin C on Infertility due to Oxidative Stress Induced by Lead and Arsenic in Male Rats

Table 1

Effect of NVC on body weight and testicular absolute and relative weights of As- and Pb-exposed rats.

GroupsInitial body weight (g)Final body weight (g)Body weight changeRight testis weight (g)Left testis weight (g)Testis index (%)

C214.0 ± 3.60239.8 ± 6.0225.8 ± 2.421.08 ± 0.0631.11 ± 0.0790.45 ± 0.011
As211.3 ± 3.20215.4 ± 7.60 a4.1 ± 4.40 a0.878 ± 0.020.84 ± 0.031 a, d0.39 ± 0.335 a
Pb218.8 ± 2.00221.5 ± 4.40 a2.7 ± 2.41 a0.928 ± 0.0230.91 ± 0.021 a0.41 ± 0.026 a
NVC213.4 ± 1.91236.11 ± 3.40 b22.71 ± 1.52 b, c1.10 ± 0.049 b1.08 ± 0.045 b0.46 ± 0.0.013 b, c
As + NVC217.4 ± 4.5231.6 ± 2.11 b14.23 ± 1.98b, c0.94 ± 0.0591.03 ± 0.0460.42 ± 0.015a, d
Pb + NVC213.4 ± 2.50229.11 ± 6.2115.71 ± 3.71b, c1.021 ± 0.631.04 ± 0.0480.44 ± 0.0.054 b

All values are presented as mean ± SEM. value <0.05; value <0.01. a, b, c, and d, respectively, are compared with C, As, Pb, and NVC groups. Final body weight and body weight changes significantly increased in the As + NVC and Pb + NVC groups compared to Pb and As groups ().