Protective Effect of Nano-Vitamin C on Infertility due to Oxidative Stress Induced by Lead and Arsenic in Male Rats
Table 1
Effect of NVC on body weight and testicular absolute and relative weights of As- and Pb-exposed rats.
Groups
Initial body weight (g)
Final body weight (g)
Body weight change
Right testis weight (g)
Left testis weight (g)
Testis index (%)
C
214.0 ± 3.60
239.8 ± 6.02
25.8 ± 2.42
1.08 ± 0.063
1.11 ± 0.079
0.45 ± 0.011
As
211.3 ± 3.20
215.4 ± 7.60 a
4.1 ± 4.40 a
0.878 ± 0.02
0.84 ± 0.031 a, d
0.39 ± 0.335 a
Pb
218.8 ± 2.00
221.5 ± 4.40 a
2.7 ± 2.41 a
0.928 ± 0.023
0.91 ± 0.021 a
0.41 ± 0.026 a
NVC
213.4 ± 1.91
236.11 ± 3.40 b
22.71 ± 1.52 b, c
1.10 ± 0.049 b
1.08 ± 0.045 b
0.46 ± 0.0.013 b, c
As + NVC
217.4 ± 4.5
231.6 ± 2.11 b
14.23 ± 1.98b, c
0.94 ± 0.059
1.03 ± 0.046
0.42 ± 0.015a, d
Pb + NVC
213.4 ± 2.50
229.11 ± 6.21
15.71 ± 3.71b, c
1.021 ± 0.63
1.04 ± 0.048
0.44 ± 0.0.054 b
All values are presented as mean ± SEM. value <0.05; value <0.01. a, b, c, and d, respectively, are compared with C, As, Pb, and NVC groups. Final body weight and body weight changes significantly increased in the As + NVC and Pb + NVC groups compared to Pb and As groups ().