Research Article

Protective Effect of Nano-Vitamin C on Infertility due to Oxidative Stress Induced by Lead and Arsenic in Male Rats

Table 5

Histological results of testicular tissue and spermatic tubule in different groups.

GroupsSeminiferous tubule diameter (μM)Tubule vacuolization (%)Seminiferous epithelium thickness (μM)Lumen diameter (μM)Pyknotic cell (%)Tubule with desquamated cells (%)Johnsen score

C473.28 ± 1.82 24.71 ± 0.420111.14 ± 1.682230.57 ± 1.5861.71 ± 0.2854.71 ± 0.56510.03 ± 0.047
As406.71 ± 413 a31.37 ± 2.20 a97.85 ± 0.857217.57 ± 1.937 a11.57 ± 1.50 a31.57 ± 2.67 a6.77 ± 0.48a
Pb397.14 ± 6.745 a30.71 ± 2.337 a98.83 ± 1.10218.58 ± 2.102 a12.28 ± 1.53 a30.51 ± 1.643 a7.35 ± 0.034a
NVC439.57 ± 2.213 b, c5.57 ± 0.649 b, c126.42 ± 14.272 b, c231.42 ± 1.445 b, c3.85 ± 0.853 b, c4.60 ± 0.565 b, c9.85 ± 0.024b
As + NVC409.28 ± 5.139 a, d19.57 ± 1.269 a, b, c, d104.85 ± 1.335221.28 ± 1.106 a, d8.42 ± 1.19 a27.85 ± 1.994 a, c, d8.69 ± 0.028a, c
Pb + NVC402.00 ± 4.654 a, d17.42 ± 1.296 a, b, c, d105.57 ± 0.812221.71 ± 2.542 a, d7.78 ± 1.01 a, d26.00 ± 1.327 a, c, d8.12 ± 0.094a, c

All values are presented as mean ± SEM. value <0.05; p value <0.01; value <0.001. a, b, c, and d, respectively, are compared with C, As, Pb, and NVC groups.