Local Gene Delivery System by Bubble Liposomes and Ultrasound Exposure into Joint Synovium
Figure 7
Immunostaining for luciferase in synovial fibroblast. Local gene expression in joint synovium after intra-articular gene delivery using BL and US. Seven days after treatment, the expression of luciferase protein was mostly limited to the synovial fibroblasts. (a) H&E staining in joint sections. (b) Immunohistochemical localization of luciferase (arrows). Scale bar = 100 μm.