Enhanced Transport Capabilities via Nanotechnologies: Impacting Bioefficacy, Controlled Release Strategies, and Novel Chaperones

Table 2

List of various “bottom up” processes and influence on particle properties.

Bottom up processes	Properties controlled
Crystallization	(i) Size, shape
	(ii) Crystalline structure—Crystalline/amorphous
	(iii) Polymorph
Precipitation	(i) Size, shape
	(ii) Surface area
Encapsulation in polymers	(i) Size, shape
	(ii) API concentration
	(iii) Particle nanostructure
Chemical reactions	(i) Size, shape
	(ii) Purity
	(iii) Surface area