Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles
Figure 5
Effect of polymer: siRNA N/P ratios on the (a) relative binding affinity, and (b) the transfection efficiency. A decrease in fluorescence intensity (on a) correlates to increased binding between polymer/siRNA complexes. Note: the relative binding affinity was measured at the 3 lowest N/P ratios for all transfectin vehicles.