Research Article

A New Application of Lipid Nanoemulsions as Coating Agent, Providing Zero-Order Hydrophilic Drug Release from Tablets

Table 3

Experimental parameters obtained from the kinetics drug release of tablets (B) (see Figure 6). The release speeds reported ( 𝑑 𝑀 𝑑 / 𝑑 𝑑 ) correspond to the linear diffusion regime.

NE-coating 𝑣 = 𝑑 𝑀 𝑑 / 𝑑 𝑑 ( 1 0 βˆ’ 5 g β‹… s βˆ’ 1 ) 𝑑 𝛼 𝐷 / 𝑅 2 ( s βˆ’ 1 )

non-coatedβ€” 19 s 0.011
2 wt.% 38.9 122 s 0.236
5.5 wt.% 7.6 11 min 2.757
6 wt.% 4.2β€”β€”
7.6 wt.% 3.6β€”β€”