Composite Polylactic-Methacrylic Acid Copolymer Nanoparticles for the Delivery of Methotrexate

<table>A computographic representation depicting (a) formation of uniform nanoparticle molecules (nucleation), (b) cluster or grouping of molecules (growth), (c) crosslinked nanoparticles, (d) ion fill with synthetic PLA/MAA cavitation, (e) MTX-PLA/MAA fill with MTX adsorption, and (f) heterogeneous fill depicting MTX loaded into the PLA/MAA composite.</table>

Journal of Drug Delivery

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Figure 14

Figure 14: Composite Polylactic-Methacrylic Acid Copolymer Nanoparticles for the Delivery of Methotrexate 