Review Article
Lipoplatin Formulation Review Article
Table 1
Pharmacokinetic parameters of total platinum in patients’ sera at the different dose levels.
| Dose | Pts | | | Cl | | | | mg/m2 | (n) | (h μg/mL) | (μg/mL) | (L/m2 h) | (L/h) | (h) | (L/m2) |
| 25 | 5 | 139.63 | 2.48 ± 1.18 | 0.18 | 0.0114 | 60.79 | 15.71 | 50 | 3 | 119.19 | 2.87 ± 0.59 | 0.42 | 0.0001 | N/A | N/A | 100 | 5 | 172.89 | 3.74 ± 1.18 | 0.58 | 0.0059 | 117.46 | 98.03 | 125 | 4 | 256.09 | 5.65 ± 2.67 | 0.49 | 0.0085 | 81.53 | 57.42 |
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N/A, not applicable.
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