Review Article

Successfully Improving Ocular Drug Delivery Using the Cationic Nanoemulsion, Novasorb

Figure 3

In vivo confocal microscopy score of rabbit ocular surface following repeated instillations with Novasorb cationic emulsion of latanoprost. IVCM images of rabbit ocular surface and conjunctiva associated lymphoid tissue (CALT) were used to assess the safety of the cationic emulsion of latanoprost by scoring the alterations observed following repeated instillations. Note that the lower the score the better the tolerance. PBS was used as a negative control. (*) 𝑃 < 0 . 0 0 0 1 compared with 0.02% BAK-latanoprost (0.005%). Adapted from Liang et al. [56].
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