A Versatile Polymer Micelle Drug Delivery System for Encapsulation and In Vivo Stabilization of Hydrophobic Anticancer Drugs

Figure 1

The IVECT polymer micelle. Drugs are loaded into the core hydrophobic block (yellow). The crosslinking block (green) provides stability to the micelle by forming pH-reversible metal-acetate bonds that allow for triggered drug release near the tumor. The PEG block (gray) gives the micelle aqueous solubility and stealth properties in vivo.