Research Article

A Versatile Polymer Micelle Drug Delivery System for Encapsulation and In Vivo Stabilization of Hydrophobic Anticancer Drugs

Figure 6

Pharmacokinetics of crosslinked BB4007431 micelles in rats. Sprague-Dawley rats were given a single intravenous administration of crosslinked BB4007431 micelle, or free BB4007431 at a 25 mg/kg dose. Plasma was analyzed for BB4007431 concentration at various timepoints. The table depicts the area under curve (AUC) and 𝐶 m a x values for each test article.
951741.fig.006