Convection-Enhanced Delivery for Targeted Delivery of Antiglioma Agents: The Translational Experience
Figure 1
(a) The local delivery of PBS for 7 days into PDGF-expression retrovirus-induced tumor (large arrow—injection site) demonstrates a large proliferative lesion with notable pseudopalisading necrosis (small arrows) and invasion across the corpus callosum (CC). (b) The delivery of topotecan for 7 days results in significant decrease in tumor cells. (Figure reprinted with permission from Lopez et al. [5].)
